OXYTOCIN

                                                      OXYTOCIN 

Oxytocin is secrreted by posterior pituitary along with vasopressin (ADH)  Pituitary extract was first used in labour in 1909. Both oxytocin and A are synthesized within the A down the axon and stored in the nerve endings within the neurohyphyosis.

OXYTOCINE -MILK-EJECULATION

ACTION

1. UTERUS:- Oxytocin increases the force and frequency uterin  contractions.WitH low doses, full relaxation occurs inbetween    contraction basal tone increases only with high doses

  .

  2. BREAST:- Oxytocin contracts myoepithelium of mammary alveoli and forces milk into the bigger milk sinusoids  milk ejuction reflex is initiated by sucklingvsothat it may be easily sucked by the infant

3. CVS:- conventional doses used in obstetrics have no effect on BP but higher doses cause vasodilation brief fall in BP , reflex techycardia and flushing

2. Milk ejection reflex:- It is mediated by oxytocin. The myoepithelial cells  breast

 4. KIDNEY:- Oxytocin in high doses exerts an ADH like action urine output is
decrease

 Physiological role

1. Labour:- Oxytocin is released during labour and the uterus is highly sensitive

to it at this time are more sebsitive than myomemetrium to oxytocin ; milk ejection reflex is absent in the hypophysectomized.

3. Neurotransmission:- Oxytocin appears to function as a peptide neurotransmitter in the hypothalamus and brainstem to regulat autonomic neurone

.
USES:-

1. Induction of labour

2. Uterine inertia

3. Postpartum haemorrhage , cesarean section

4. Breast engorgement

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Milan Tomic

Hi. I’m Designer of Blog Magic. I’m CEO/Founder of ThemeXpose. I’m Creative Art Director, Web Designer, UI/UX Designer, Interaction Designer, Industrial Designer, Web Developer, Business Enthusiast, StartUp Enthusiast, Speaker, Writer and Photographer. Inspired to make things looks better.

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